CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);UNIVERSITE CLAUDE BERNARD LYON I
发明人:
ALAIN DOMARD,FLORENCE DUPASQUIER,LAURENT DAVID
申请号：
BRPI0817567
公开号：
BRPI0817567B1
申请日:
2008.09.26
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
The present invention relates to a method for preparing by wet spinning a continuous filament based on hyaluronic acid in free acid form, notably soluble in water. The preparation method according to the invention comprises the following steps: a) preparing a spinnable aqueous solution of hyaluronic acid or of a hyaluronic acid salt, preferably a sodium hyaluronate solution； b) extruding said solution to an extrusion die； c) forming the filament by passing the extruded solution into a bath of acetic acid, concentrated to more than 80%, drawing and drying. The invention also relates to a filament based on hyaluronic acid in free acid form, said filament having swelling properties in water and physiological liquids and moreover being solubilizable in water under certain conditions.
