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oleyl phosphocholin solid dosage form for oral administration, solid dosage form, and method for preparing a solid dosage form
专利权人:
DAFRA PHARMA RESEARCH & DEVELOPMENT BVBA
发明人:
FRANS HERWIG JANSEN
申请号:
BR112013012652
公开号:
BR112013012652A2
申请日:
2011.11.21
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The present invention relates to solid dosage forms of oleyl phosphocholine (C18:1-PC), or OlPC, for oral administration. Further, the present invention relates to methods for the preparation of the present solid dosage forms and the use thereof as a medicament and especially a medicament for treatment of parasitic diseases, such as leishmaniasis, chagas and malaria, and cancer both in humans and animals. Specifically, the present invention relates to a solid dosage form comprising: 6 to 25 weight % of the solid dosage form oleyl phosphocholine; 20 to 35 weight % of the solid dosage form lactose; 35 to 50 weight % of the solid dosage form cellulose; 5 to 20 weight % of the solid dosage form croscarmellose; 1 to 10 weight % of the solid dosage form hydroxypropylmethyl cellulose; and 0.05 to 1 weight % of the solid dosage form of a lubricant.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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