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TREATMENT OF COGNITIVE DISORDERS (R) -7-chloro-N- (quinuclidin-3-YL) BENZO [B] THIOPHENE-2-carboxamide and its pharmaceutically acceptable salts
专利权人:
ЭНВИВО ФАРМАСЬЮТИКАЛЗ, ИНК.
发明人:
КЕНИГ Герхард,ЧЕСУОРТ Ричард,ШАПИРО Гидеон
申请号:
RU2011124515
公开号:
RU2011124515A
申请日:
2009.11.19
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A method of improving cognition, comprising administering (R) -7-chloro-N- (quinuclidin-3-yl) benzo [b] thiophene-2-carboxamide or a pharmaceutically acceptable salt thereof in a daily dose of less than 3 mg.2. A method according to claim 1, wherein the daily dose is 1 mg or menee.3. A method according to claim 2, wherein the daily dose is 0.3 mg or menee.4. A method of treating cognitive disorders comprising administering to a patient (R) -7-chloro-N- (quinuclidin-3-yl) benzo [b] thiophene-2-carboxamide or a pharmaceutically acceptable salt thereof in a daily dose of less than 3 mg.5. A method according to claim 4, wherein the daily dose is 1 mg or menee.6. A method according to claim 5, wherein the daily dose is 0.3 mg or menee.7. A method of treating a disorder selected from schizophrenia, schizophreniform disorder, schizoaffective disorder, and delusional disorder comprising administering to a patient (R) -7-chloro-N- (quinuclidin-3-yl) benzo [b] thiophene-2-carboxamide or a pharmaceutically acceptable salt thereof in a daily dose of less than 3 mg.8. A method according to claim 7 wherein the daily dose is 1 mg or menee.9. The method of claim 8 wherein the daily dose is 0.3 mg or menee.10. A method for improving one or more of: learning, memory latency, memory, visual learning, speed of processing, vigilance, verbal learning, visual motor function, social cognition, long term memory, executive function, comprising administering (R) -7-chloro- N- (quinuclidin-3-yl) benzo [b] thiophene-2-carboxamide or a pharmaceutically acceptable salt thereof in a daily dose of less than 3 mg.11. A method according to claim 10, wherein the daily dose is 1 mg or menee.12. The method of claim 11 wherein the daily dose is 0.3 mg or menee.13. A method of improving1. Способ улучшения познания, включающий введение пациенту (R)-7-хлор-N-(хинуклидин-3-ил)бензо[в]тиофен-2-карбоксамида или его фармацевтически приемлемой соли в суточной дозе менее 3 мг.2. Способ по п.1, в котором суточн
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