Mark Moran;Anjali Kumar;Neil Bodick;Robert C. Blanks;Michael D. Clayman
发明人:
Neil Bodick,Robert C. Blanks,Anjali Kumar,Michael D. Clayman,Mark Moran
申请号：
US13368580
公开号：
US20120282298A1
申请日:
2012.02.08
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Corticosteroid microparticle formulations are provided for use for treating pain, including pain caused by inflammatory diseases such as osteoarthritis or rheumatoid arthritis, and for slowing, arresting or reversing structural damage to tissues caused by an inflammatory disease, for example damage to articular and/or peri-articular tissues caused by osteoarthritis or rheumatoid arthritis. Corticosteroid microparticle formulations are administered locally as a sustained release dosage form (with or without an immediate release component) that results in efficacy accompanied by clinically insignificant or no measurable effect on endogenous cortisol production.
