#$%^&*AU2016231461A120161006.pdf#####REPLACEABLE STAPLE CARTRIDGE ABSTRACT A cartridge assembly (140) that can be removed from an instrument (100) and replaced, the cartridge assembly (140) having a lockout for preventing advancement of a drive assembly (50) having a knife (52), the lockout having a pair of interlocking plates (150) adjacent the distal end (50b) of the drive assembly (50) when in the initial position, the drive assembly (50) having a chamfered proximal edge for moving the interlocking plates (150) away as the drive assembly (50) is retracted.