Daniel L. Flynn,Michael D. Kaufman,Thiwanka Samarakoon,Timothy Malcolm Caldwell,Lakshminarayana Vogeti,YuMi Ahn,William C. Patt,Karen M. Yates
申请号:
US14214134
公开号:
US09133183B2
申请日:
2014.03.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Described are compounds of Formula Iwhich find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-1R), c-KIT, and/or PDGFR kinases. These compounds also find utility in the treatment of other mammalian diseases mediated by c-FMS, c-KIT, or PDGFR kinases.