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NOUVEAU COMPOSÉ AYANT UNE STRUCTURE 3-HÉTÉROARYLPYRIMIDIN-4-(3H)-ONE ET PRÉPARATION PHARMACEUTIQUE CONTENANT CELUI-CI
专利权人:
Kowa Company; Ltd.
发明人:
申请号:
EP10764287.8
公开号:
EP2420501A1
申请日:
2010.04.16
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Disclosed is a compound which has both an angiotensin-II receptor antagonistic activity and a PPARγ activation activity and is useful as a prophylactic and/or therapeutic agent for hypertension, heart diseases, angina pectoris, cerebrovascular disorders, cerebral circulatory disorders, ischemic peripheral circulatory disorders, renal diseases, arteriosclerosis, inflammatory diseases, type-2 diabetes, diabetic complications, insulin resistance syndrome, syndrome X, metabolic syndrome and hyperinsulinemia. [In the formula, A represents a 5- to 10-membered heteroaryl group; R1 and R2 independently represent a C1-6 alkyl group; and each of R3 to R5 is absent or represents H, a halogen atom, OH, NO2, a halo-C1-6 alkyl group, a (substituted) C1-6 alkoxy group, a (substituted) C3-6 cycloalkyloxy group, or a 5- to 10-membered heteroaryl group.]
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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