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High-molecular weight conjugate of steroids
专利权人:
Masayuki Kitagawa
发明人:
Masayuki Kitagawa,Toshitaka Murata
申请号:
US12678620
公开号:
US08703878B2
申请日:
2008.09.26
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Enzymes in the body vary among different species, and also vary among individuals of the same species. Thus, it has been demanded to develop a novel steroid-containing pharmaceutical preparation which can release a drug in a manner independent of the enzymes present in the body, and which is expected to have an efficacious therapeutic effect.Disclosed is a high-molecular weight conjugate of a steroid, comprising a structure in which a carboxylic acid group of a polymer having a polyethylene glycol moiety and a succinic acid monoamide moiety having two or more succinic acid monoamide units is ester-bonded to a hydroxy group in the steroid.
来源网站:
中国工程科技知识中心
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