ANTICORPS DIRIGE CONTRE RGD DANS UNE SEQUENCE D'ACIDES AMINES D'UNE PROTEINE DE MATRICE EXTRACELLULAIRE ET PROCEDE DE FABRICATION ET UTILISATION DE CELUI-CI
The present invention provides a monoclonal antibody which specificallyrecognizes RGD in the amino acid sequence of extracellular matrix proteins ofa humanand a mouse. By specifically inhibiting the RGD sequence-mediated adhesion,exertion of efficient effects on diseases such as inflammation, cancer,infectious disease,autoimmune diseases and osteoporosis and reduction in adverse effects can beexpectedat the same time. Therefore, better treatment methods can be provided to thesediseases.