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ISOLATION, CHARACTERIZATION AND EVALUATION OF ANTI HEPATOTOXIC PROPERTY OF A NOVEL COMPOUND FLAVARIOPYRANOSTEROL FROM FLAVERIA TRINERVIA C. MOHR
专利权人:
发明人:
PROF V KRISHNA,MR SURESH BABU P
申请号:
IN1460/CHE/2009
公开号:
IN2009CH01460A
申请日:
2009.06.22
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
A new compound referred to as Flavariopyranosterol (a new name given by the inventor), a steroidal glucoside, is isolated from petroleum ether extract of whole plant of eleaveria trinervia (Asteraceae). Various biochemical and histological tests, conducted using albino mice as test animals, have shown that this new compound exhibits significant hepatoprotectivity (anti-hepato toxicity properties). With the help of spectroscopic studies and chem-informatics tools, the structure of this compound has been found to be 5- (17-hydroxy-4,4-dimethyl-2,3,4,5,6,7,8, 9,10,11,12,13,14,15,16,17-tetradecahydro-1 H-cyclopenta[alpha]phenanthren-3-yloxy)-6- hydroxy methyl-tetrahydro-pyran-2,3,4-triol. Its The hepatoprotectivity is confirmed by restoration of levels of liver function markers and hepatic architecture towards normal condition. This property of Flaveriophyranosterol is a good choice of hepatoprotective drug for treatment of jaundice.
来源网站:
中国工程科技知识中心
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