PROTEIN-ASSISTED DRUG DELIVERY SYSTEM FOR THE TARGETED ADMINISTRATION OF ACTIVE AGENTS FOR OVERCOMING BLOOD-BRAIN BARRIER

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专利权人:

发明人:

申请号：

EP10716435.2

公开号：

EP2413904A1

申请日:

2010.03.29

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention provides a composition and prodrug for targeted drug delivery to the central nervous system of a patient. The inventive composition and prodrug include a pharmaceutically acceptable active agent and at least one protein selected from the group consisting of a fimbrial adhesin protein, a membrane protein, and combinations thereof. The inventive compositions and prodrugs of the present invention selectively target the blood-brain barrier and deliver hydrophilic and lipophilic active agents of varying sizes to the central nervous system.

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