Fluorine-substituted indazole compounds, pharmaceutical compositions containing these compounds and uses thereof. The compounds and pharmaceutical compositions can be used as soluble guanylate cyclase simulators.本發明涉及一種氟取代的吲唑類化合物及其用途,進一步涉及包含所述化合物的藥物組合物。本發明所述化合物或所述藥物組合物可以用作可溶性鳥苷酸環化酶刺激劑。