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Methods for treating cancer using 3 - (5 - amino - 2 - methyl - 4 - oxo 4H - quinazolin - 3 - il) piperidin - 2.6 - dione
专利权人:
CELGENE CORPORATION
发明人:
申请号:
ARP120100782
公开号:
AR085651A1
申请日:
2012.03.09
申请国别(地区):
AR
年份:
2013
代理人:
摘要:
Methods to treat, prevent and / or control cancer, comprising administering to a patient (3 - 5 - methyl - 2 - amino - 4 - oxo 4H - quinazolin - 3 - il) piperidin - 2.6 - dione, or an enantiomer or a mixture of Enantiomers of the same, or Salt acceptable to use Pharmaceutical Co Crystal solvate, hydrate, cla Treatment, polymorphic or pharmaceutically acceptable.Claim 1: a method for treating or Controlling cancer, characterized in that it comprises administering to a patient in need of such treatment or control an effective amount for Therapeutic use of 3 - (5 - amino - 2 - methyl - 4 - oxo 4H - quinazolin - 3 - il) piperidin - 2.6 - dione, which has The struct. Ra of formula (1), or a mixture of enantiomers or enantiomer thereof,Acceptable for pharmaceutical use, or a Salt, solvate, hydrate, co Crystal, clathrate, or Polymorph thereof.Claim 2: the method of claim 1, wherein the Cancer is Advanced malignancy, amyloidosis, neuroblastoma, meningioma, hemangiopericytoma, multiple Brain metastasis, glioblastoma multiforme glioblastoma, a brain stem glioma, malignant brain tumor with Poor prognosis, malignant glioma, anaplastic astrocytoma, anaplastic oligodendroglioma.Neuroendocrine tumor, rectal adenocarcinoma, colorectal cancer of Dukes C and D, inoperable metastatic colorectal Carcinoma, hepatocellular carcinoma, Kaposi's Sarcoma, acute myeloblastic Leukemia karyotype, Hodgkin's Lymphoma, non hodgkin lymphoma, cutaneous t-cell Lymphoma, gra T cells in diffuse low-grade, follicular Lymphoma, malignant melanoma, malignant mesothelioma,Syndrome with pleural effusion of malignant mesothelioma, peritoneal Carcinoma, papillary serous Carcinoma, sarcoma, gynaecological, soft tissue sarcoma, scleroderma, cutaneous vasculitis, Langerhans Cell Histiocytosis, leiomyosarcoma, Fibrodysplasia ossificans progressiva, Prosperous cancer Tata Hormone Refractory soft tissue sarcoma, high-risk Surgery.Inoperable hepatocellular carcinoma, Waldenstrom's macroglobulinemia, Multiple Myelom
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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