PARK, DAE SUNGKR,박대성,BAE, IN HOKR,배인호,SHIM, JAE WONKR,심재원,LEE, SO YOUNKR,이소연,JANG, EUN JAEKR,장은재,LIM, KYUNG SEOBKR,임경섭,PARK, JUN KYUKR,박준규,KIM, IN SOOKR,김인수,SIM, DOO SUNKR,심두선,JEONG, MYUNG HOKR,정명호
申请号：
KR1020160067475
公开号：
KR1016535350000B1
申请日:
2016.05.31
申请国别(地区):
KR
年份:
2016
代理人:
摘要：
A drug elution stent for a blood vessel of the present invention can precisely control the total content of bound everolimus-based drugs and has effects in forming a uniform layer, even if a polymer causing post-thrombotic syndrome or the like, by using electrospinning. The drug elution stent comprises: a stent a nitrogen-doped titanium oxide layer formed on the stent a surface-coupled functional group including a hydroxyl group and ester-bound everolimus-based drugs and physically-bound everolimus-based drugs, bound to the surface-coupled functional group.COPYRIGHT KIPO 2016본 발명의 혈관용 약물 용출 스텐트는 전기방사가 이용됨으로써, 후기 혈전증 등을 유발할 수 있는 고분자가 사용되지 않음에도 결합된 에버롤리무스계 약물의 총 함량을 정밀하게 제어할 수 있으며, 균일한 층을 형성할 수 있는 효과가 있다.
