PROCESS FOR THE PREPARATION OF N - [(2'R) -2'-deoxy-2'-fluoro-2'-METHYL-PHENYL-P-5 'URIDYLYL] -L-alanine 1-METHYL ETHYL ESTER

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专利权人:

Gilead Pharmasset LLC

发明人:

ROSS, Bruce, S.,SOFIA, Michael, Joseph,PAMULAPATI, Ganapati, Reddy,RACHAKONDA, Suguna,ZHANG, Hai-ren,CHUN, Byoung-Kwon,WANG, Peiyuan

申请号：

DK10721225

公开号：

DK2432792T3

申请日:

2010.05.20

申请国别(地区):

DK

年份:

2016

代理人:

摘要：

Disclosed herein are nucleoside phosphoramidates of formula 4 and their use as agents for treating viral diseases. These compounds are inhibitors of RNA-dependent 5 RNA viral replication and are useful as inhibitors of HCV NS5B polymerase, as inhibitors of HCV replication and for treatment of hepatitis C infection in mammals.

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中国工程科技知识中心

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http://www.ckcest.cn/home/