GURNEY, AUSTIN, L.,SATO, AARON, KEN,BOND, CHRISTOPHER, JOHN
申请号：
SG11201400870W
公开号：
SG11201400870WA
申请日:
2012.09.24
申请国别(地区):
SG
年份:
2014
代理人:
摘要：
The present invention relates to VEGF-binding agents, DLL4-binding agents, VEGF/DLL4 bispecific binding agents, and methods of using the agents for treating diseases such as cancer. The present invention provides antibodies that specifically bind human VEGF, antibodies that specifically bind human DLL4, and bispecific antibodies that specifically bind human VEGF and/or human DLL4. The present invention further provides methods of using the agents to inhibit tumor growth. Also described are methods of treating cancer comprising administering a therapeutically effect amount of an agent or antibody of the present invention to a patient having a tumor or cancer.
