CHAND, DHAN SIDHARTHA,WILSON, NICHOLAS STUART,UNDERWOOD, DENNIS JOHN,MORIN, BENJAMIN MAXIME
申请号：
CA3062061
公开号：
CA3062061A1
申请日:
2018.05.01
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The instant disclosure provides antibodies that specifically bind to T-cellimmunoreceptor with Ig and ITIM domains(TIGIT) (e.g., human TIGIT) and antagonize TIGIT function. Also provided arepharmaceutical compositions comprising theseantibodies, nucleic acids encoding these antibodies, expression vectors andhost cells for making these antibodies, and methods of treatinga subject using these antibodies.
