INDUSTRY-ACADEMIC COOPERATION FOUNDATION; CHOSUN UNIVERSITY
发明人:
KIM, CHUN SUNGKR,김춘성,MOON, SUNG MINKR,문성민
申请号：
KR1020140068507
公开号：
KR1020150140129A
申请日:
2014.06.05
申请国别(地区):
KR
年份:
2015
代理人:
摘要：
The present invention relates to an active composition for anti-cancer cell extinction containing an Anthriscus sylvestris Hoffmann extract. MTT assay, DNA fragmentation, western blot and LIVE-DEAD cell staining after treating a methanol extract of Anthriscus sylvestris Hoffmann in oral cancer cells (KB cell line) are performed in order to investigate an effect of the Anthriscus sylvestris Hoffmann methanol composition of the present invention on the oral cancer cells, and find out an effect of growth inhibition, and a molecular mechanism of cancer cell growth inhibition and apoptosis and, consequently, the composition of the present invention has an effect capable of separating single or composite ingredients having anticancer activity in the oral cancer cells.COPYRIGHT KIPO 2016본 발명의 전호 메탄올 조성물이 구강암세포에 미치는 영향을 조사하고 성장 억제에 미치는 효과와 암세포 성장억제 및 세포사멸에 대한 분자적 기전을 규명하고자 전호 메탄올 추출물을 구강암세포(KB 세포)에 처리한 후 MTT assay, DNA fragmentation, western blot 및 LIVE-DEAD cell staining등을 수행하여 조사한 결과 본 발명의 조성물은 이용하여 구강암세포에 항암활성을 갖는 단일 및 복합성분을 분리할 수 있는 효과가 있다.
