Exemplary systems, methods and computer-accessible mediums can be provided that can, for example, receive information related to a detection of a pulse of a patient(s), and increase a pressure using a hardware arrangement to reach a first pressure level corresponding to the pulse no longer being detected. The pressure can be decreased to reach a second pressure level corresponding to the pulse being again detected, and the pressure can be maintained at the second pressure level to facilitate a venipuncture of the patient(s).
