Emmanuel Nony;Nicolas Bihoreau;Roland Beliard;Arnaud Glacet;Dominique Bourel;Christophe de Romeuf
发明人:
Roland Beliard,Dominique Bourel,Arnaud Glacet,Christophe de Romeuf,Nicolas Bihoreau,Emmanuel Nony
申请号:
US12502911
公开号:
US08124078B2
申请日:
2009.07.14
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention concerns a method for obtaining and selecting monoclonal antibodies by an ADDC-type test, said antibodies capable of activating type III Fcγ receptors and having a particular glycan structure. The inventive anti-D antibodies can be used for preventing Rhesus isoimmunization in Rh negative persons, in particular for haemolytic disease in a new-born baby or for uses such as idiopathic thrombocytopenic purpura (ITP).