您的位置: 首页 > 农业专利 > 详情页

Inhibitors of diacylglycerol O-acylotransferase type 1 enzyme
专利权人:
ABBOTT LABORATORIES
发明人:
SOUERS, ANDREW J
申请号:
NZ59724707
公开号:
NZ597247A
申请日:
2007.11.26
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
597247 Disclosed are compounds of formula (I) where A is either triazoyl, pyrazaoyl or imidazol[1,2-a]pyrimidinyl. Examples of compounds of formula (I) are: 2-{ 4-[4-(1H-1,2,4-triazol-3-yl)phenyl]cyclohexyl} propanoic acid Trans ethyl { 4-[4-(5-aminoimidazol[1,2-a]pyrimidin-6-yl)phenyl]cyclohexyl} acetate and { 4-[5-(5-{ [2-(trifluoromethoxy)benzyl]oxy} -1H-pyrazol-3-yl)pyridin-2-yl]cyclohexyl} acetic acid. Also disclosed are compositions comprising compounds of formula (I) and the use of compounds of formula (I) in the manufacture of a medicament for the treatment of a disorder selected from the group consisting of type 2 diabetes, obesity, elevated plasma triglycerides, metabolic syndrome, non-alcoholic steatohepatitis, and non-alcoholic fatty liver disease in a subject in need thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充