Graham Beaton,Fabio C. Tucci,Satheesh B. Ravula,Chandravadan R. Shah,Hiep Luu
申请号:
US16000283
公开号:
US10570103B2
申请日:
2018.06.05
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A method for treating a lysophosphatidic acid-dependent disease or condition in a subject in need thereof is provided. The method includes administering to the subject a therapeutically effective amount of a heterocyclic compound. The heterocyclic compound is a lysophosphatidic acid receptor ligand. Lysophosphatidic acid-dependent diseases and conditions include diseases involving fibrosis, such as fibrosis of the heart, kidney, liver and lung, and scleroderma; inflammatory diseases such as diabetic nephropathy and inflammatory bowel disease; ocular diseases such as diseases involving retinal degeneration; nerve diseases such as pruritus and pain.