Storz, Thomas,Medina, Julio C.,Milne, Jacqueline,Grillo, Mark,Wang, Yingcai,Su, Yongli,Payack, Joseph F.,Jona, Janan,Li, An-Rong,Murry, Jerry,Liu, Jiwen,Allgeier, Alan
申请号：
AU2008343924
公开号：
AU2008343924B2
申请日:
2008.12.18
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of inflammatory and immune-related diseases and conditions. In particular, the invention provides compounds which modulate the function and/or expression of proteins involved in atopic diseases, inflammatory conditions and cancer. The subject compounds are carboxylic acid derivatives of formula I wherein R1 is alkyl or cycloalkyl； R2 is halo, alky I, haloalkyl, alkoxy, haloalkoxy or cycloalkyl； and X is chloro or fluoro.
