Bemis, Jean,Nunes, Joseph J.,Disch, Jeremy S.,Armistead, David,Milne, Jill,Xie, Roger,Salzmann, Thomas,Ng, Pui Yee,Vu, Chi B.
申请号：
AU2006278397
公开号：
AU2006278397B2
申请日:
2006.08.04
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
Provided herein are oxazolopyridine derivatives which are sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasingthe lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benfêt from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
