William Godwin ATTERBURY,Corrie Jo BENNISON,Robert Jonathan CAIN,Michael Funk CHIAPPETTA,Jeffrey LeClair ELLIS,David Arthur HOLLEY,Mark LAFEVER,Beverly Ann PIATT,John Paul TALLARICO
申请号：
US16484676
公开号：
US20200030537A1
申请日:
2018.02.09
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Processes and devices are disclosed for parenteral delivery of therapeutic fluids, in particular high-viscosity therapeutic fluids (e.g., protein therapeutics), by a chemical reaction that generates a gas. The device may include a first actuation chamber containing a first reagent, a second reaction chamber containing a second reagent, and a third therapeutic fluid chamber containing the therapeutic fluid. In a loaded configuration, a plunger separates the first chamber from the second chamber. In a delivery configuration, the plunger allows the first reagent from the first chamber to communicate and react with the second reagent from the second chamber. The generated gas acts upon a plunger to deliver the therapeutic fluid from the third chamber.
