The present invention is directed to the combination of biopesticide and at least one exogenous cuticle degrading enzymes (e.g., a protease, chitinase, lipase and/or cutinase) for controlling (preventing or eliminating) pests. The use of an exogenous cuticle degrading enzyme increases the efficacy of the biopesticide by increasing the speed and/or efficiency of infestation of the pest resulting in faster or more effective killing or disabling of the pest by the biopesticide. The present invention accordingly provides methods for controlling a pest comprising treating a pest habitat with a combination of pesticidally effective amounts of at least one biopesticide and at least one exogenous cuticle degrading enzyme. Pest control compositions are also described.