T-cell receptor (TCR)-binding antibodies and uses thereof

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专利权人:

THE UNIVERSITY OF TEXAS SYSTEM;BOARD OF REGENTS

发明人:

Laurence J. N. Cooper,Bipulendu Jena

申请号：

US15759148

公开号：

US10633445B2

申请日:

2016.09.15

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Antibodies and antigen binding fragments thereof are provided that bind to T-cell receptors (e.g., TCRα), essentially independent of T-cell epitope specificity. Methods for manipulation of T-cells and methods of treatment using such antibodies are likewise provided.

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http://www.ckcest.cn/home/