PROBLEM TO BE SOLVED: To provide a drug which inhibits the BAFF binding to a BR3 receptor and has excellent preventing and treating effects on autoimmune diseases, acquired immunodeficiency syndrome, and non-Hodgkin lymphoma.SOLUTION: The BAFF binding inhibitor to a BR3 receptor includes a compound represented by formula (1) (wherein R1 is a 1-10C alkyl group and R2, R3, R4, and R5 may be the same as or different from one another and are each hydrogen or a hydroxyl group), a salt thereof or a solvate thereof as an active ingredient.COPYRIGHT: (C)2012,JPO&INPIT【課題】BR3受容体に対するBAFFの結合を阻害し、自己免疫性疾患、後天性免疫不全症候群、非ホジキンリンパ腫の予防及び治療効果に優れた薬剤を提供すること。【解決手段】次の一般式(1):[式中、R1はC1-10アルキル基を示し、R2、R3、R4、R5は、互いに同一又は異なっていてもよく、水素原子又は水酸基を示す。]で表される化合物、若しくはその塩、又はそれらの溶媒和物を有効成分として含有することを特徴とするBR3受容体に対するBAFFの結合阻害剤。【選択図】なし
