TURNER RACHAEL,LOZOYA OSWALDO,REID LOLA M.,GERBER DAVID
申请号：
NZ60391311
公开号：
NZ603913A
申请日:
2011.05.06
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Discloses use of a mixture for the manufacture of a medicament for engrafting liver cells into a liver in a diseased or dysfunctional condition in a subject, the mixture comprising: a. normal liver or biliary tree cells wherein the cells are not human totipotent cells； b. combined with endothelial cell precursors, stellate cell precursors and one or more biomaterials to form a mixture； c. optionally, the mixture is combined with nutrient medium, signalling molecules, extracellular matrix components, or a combination thereof； wherein upon introducing the mixture of step (b) or (c) into the liver of the subject, a substantial portion of the cells introduced take up residence in or on at least a portion of the liver in vivo. Also discloses similar methods for repairing tissue and localising cells to a surface.
