Marcela De Leon Gatti,Yingqing Huang,David K. Schisla,Lou-Hwa J. Sheu,Christopher A. Tomas
申请号：
US13773192
公开号：
US10023607B2
申请日:
2013.02.21
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A method for separating a biological conjugate from an aggregate. The molecular weight of the biological conjugate ranges from about 10 kDa to about 1000 kDa. In one embodiment, the method comprises the steps of:(e) providing a mixture comprising the biological conjugate and the aggregate, wherein the biological conjugate has a molecular weight of from about 10 kDa to about 1000 kDa；(f) providing a chromatography column containing a gel, wherein the gel comprises at least one polysaccharide；(g) introducing the mixture of step (a) into the chromatography column；(h) recovering the biological conjugate from the column.
