Pierre FONS;Alexandre FROIDBISE;Philippe DUCHAUSSOY
发明人:
Philippe DUCHAUSSOY,Pierre FONS,Alexandre FROIDBISE
申请号：
US13369677
公开号：
US20120202769A1
申请日:
2012.02.09
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to FGF receptor-activating N-sulfate oligosaccharides having Formula (I), wherein R1, R4, R6, and R8 are —OSO3− or hydroxyl groups, R2 is an —O-alkyl group or a monosaccharide having Formula (II), R3 is a disaccharide having Formula (III), R5 is a disaccharide having Formula (IV), R7 is a hydroxyl group or a disaccharide having Formula (VI), and R9 is a hydroxyl or —O-alkyl group or a disaccharide having Formula (VII), where R10- is an —O-alkyl group. The invention further relates to the preparation of said oligosaccharides and to the therapeutic use thereof.
