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THIENO-PYRIDINE DERIVATIVES AS MEK INHIBITORS
专利权人:
Judi Charlotte Neuss;Clive Martin Hutchings;Jeremy Martin Davis;Daniel Christopher Brookings;James Andrew Johnson;Barry John Langham;Sarah Catherine Archibald
发明人:
Clive Martin Hutchings,Sarah Catherine Archibald,Daniel Christopher Brookings,Jeremy Martin Davis,James Andrew Johnson,Barry John Langham,Judi Charlotte Neuss
申请号:
US13604282
公开号:
US20120329774A1
申请日:
2012.09.05
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A series of thieno[2,3-b]pyridine derivatives which are substituted in the 2-position by a substituted anilino moiety, being selective inhibitors of human MEK (MAPKK) enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, proliferative (including oncological) and nociceptive conditions.
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