Alshad S. Lalani;Paul Westberg;John Curd;John F. W. Keana
发明人:
John F. W. Keana,Paul Westberg,John Curd,Alshad S. Lalani
申请号：
US12563543
公开号：
US08410075B2
申请日:
2009.09.21
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Disclosed are Mannich base N-oxides of drugs containing acidic N—H groups. Pharmaceutical compositions comprising a therapeutically effective amount of Mannich base N-oxides, or a N-oxide rearrangement product, pharmaceutically acceptable salt or prodrug thereof, are also disclosed. Further, disclosed are methods of using the compounds, alone or in combination with one or more other active agents or treatments.
