A method of introducing a vapor of at least one substance into an inhalation flow path of a respiratory organ is provided. The method describes providing a carrier conformable to a surface of skin； providing the carrier with at least one substance； providing a barrier coupled to a surface of the carrier, the barrier being substantially impermeable to the substances carried by the carrier； providing a polyethylene coated material disposed within or atop the barrier and configured as a clamp for a septum of a user, wherein the polyethylene coated material is heat sealed within the barrier； and engaging the carrier to the surface of skin proximate an inhalation flow path of a respiratory organ with the barrier adapted to be interposed between the carrier and the skin to prevent the one or more substances from contacting the skin； wherein the substance is non-volatile. A vehicle and mask for introducing a vapor are also provided.
