Robert Davidson,Tillman Gerngross,Stefan Wildt,Byung-Kwon Choi,Juergen Hermann Nett,Piotr Bobrowicz,Stephen Robin Hamilton
申请号：
US12840529
公开号：
US08815544B2
申请日:
2010.07.21
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides a novel lower eukaryotic host cell producing human-like glycoproteins characterized as having a terminal β-galactose residue and essentially lacking fucose and sialic acid residues. The present invention also provides a method for catalyzing the transfer of a galactose residue from UDP-galactose onto an acceptor substrate in a recombinant lower eukaryotic host cell, which can be used as a therapeutic glycoprotein.
