PROBLEM TO BE SOLVED: To provide novel compounds, and pharmaceutical compositions comprising the compounds, useful in treating a disorder or disease in which aberrant Wnt signaling is implicated, such as cancer, pulmonary fibrosis, idiopathic pulmonary fibrosis, diabetic retinopathy, rheumatoid arthritis, scleroderma, mycotic and viral infections, osteochondropathy, Alzheimer's disease, dementia, and Parkinson's disease.SOLUTION: The present invention provides: compounds having a 1H-pyrazolo[3,4-b]pyridine skeleton represented by the compound in the figure； and pharmaceutical compositions comprising the compounds.SELECTED DRAWING: None【課題】癌、肺線維症、突発性肺線維症、糖尿病性網膜症、関節リウマチ、強皮症、真菌又はウイルス感染症、骨又は軟骨疾患、アルツハイマー病、認知症、パーキンソン病など、異常なＷｎｔシグナル伝達が関係する障害又は疾患を処置に有用な新規化合物、及び該化合物を含有する医薬組成物の提供。【解決手段】下記化合物を代表例とする１Ｈ－ピラゾロ［３，４－ｂ］ピリジン骨格を有する化合物、及び該化合物を含有する医薬組成物。【選択図】なし
