FREEZE-DRIED PREPARATION OF TETRODOTOXIN AND THE PRODUCING METHOD THEREOF

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专利权人:

XIAMEN ZHAOYANG BIOLOGICAL ENGINEERING CO., LTD.;THE THIRD INSTITUTE OF OCEANOGRAPHY, STATE OCEANIC ADMINISTRATION, PEOPLE'S REPUBLIC OF CHINA

发明人:

YI, RUIZAO,CHEN, HUI,HONG, BIHONG,XIE, RONGWEI,CHEN, WEIZU,HONG, ZHUAN,XU, SHUZHEN

申请号：

MYPI 2011001176

公开号：

MY159739A

申请日:

2009.09.17

申请国别(地区):

MY

年份:

2017

代理人:

摘要：

A STABLE FREEZE-DRIED PREPARATION OF TETRODOTOXIN AND THE PRODUCING METHOD THEREOF.THE FREEZE-DRIED PREPARATION HAS TETRODOTOXIN AS THE MAIN ACTIVE INGREDIENT, AND COMPRISES SOLUBILIZER, EXCIPIENT AND STABILIZER.THE SAID SOLUBLIZER IS CITRIC ACID.THE EXCIPIENT IS SODIUM, MANNITOL OR THEIR COMPOSITE.THE STABILIZER IS DEXTRAN, TREHALOSE OR THEIR COMPOSITE.THE RATIO OF TETRODOTOXIN, EXCIPIENT AND STABILIZER IS 1:150-3000:50-500 OR 50-6000. PREFERABLY, THE PREPARATION COMPRISES LIDOCAINE HYDROCHLORIDE AS FUNCTION MODULATOR. THE PREPARATION OF THE PRESENT INVENTION CAN BE USED FOR BLOCKING THE DEPENDENCE/WITHDRAWAL SYNDROME OF DRUGS SUCH AS OPTIUMS AND CANNABIS.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/