Thomas P. Loisel;Isabelle Lemire;Guy Boileau;Philippe Crine
发明人:
Philippe Crine,Guy Boileau,Isabelle Lemire,Thomas P. Loisel
申请号：
US12638527
公开号：
US10000532B2
申请日:
2009.12.15
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A bone delivery conjugate having a structure selected from the group consisting of: A) X-Dn-Y-protein-Z； and B) Z-protein-Y-Dn-X, wherein X is absent or is an amino acid sequence of at least one amino acid； Y is absent or is an amino acid sequence of at least one amino acid； Z is absent or is an amino acid sequence of at least one amino acid； and Dn is a poly aspartate wherein n=10 to 16. Compositions comprising same and methods of use thereof.
