The University of Vermont and State Agriculture College
发明人:
Mann, Kenneth G.,Parhami-Seren, Behnaz,Fass, David N.
申请号:
AU2006270168
公开号:
AU2006270168B2
申请日:
2006.07.13
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Disclosed are antibodies that selectively bind to blood coagulation factorFVIII and highly sensitive immunological assays comprising these antibodies.Preferred assays can detect FVIII at about 3500-fold below the normal physiologicallevels, and have a wide array of applications including accurate monitoringof FVIII concentration in pharmaceutical products for treatment of blood coagulationdisorders, and determination of FVIII levels in plasma of human patients, includingthose with blood coagulation disorders such as hemophilia.