Laura J. Niedernhofer,Mitra Lavasani,Paul D. Robbins,Johnny Huard
申请号:
US13912927
公开号:
US09295696B2
申请日:
2013.06.07
申请国别(地区):
US
年份:
2016
代理人:
摘要:
This invention relates to the use of autologous stem/progenitor cells to restore or rejuvenate adult stem cell function in a mammal, wherein the restoration or rejuvenating extends lifespan and/or improves health of the mammal. In addition, the invention also relates to compositions containing one or more regulatory factors secreted or released from isolated mammalian stem/progenitor cells and use of such compositions to extend lifespan and/or improve health of a mammal. Also provided are methods of treating, delaying, preventing or reversing progeria or related syndromes in a mammal using isolated autologous or allogeneic stem/progenitor cells and/or regulatory factors secreted or released therefrom.