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antibody or antibody fragment, antibody or isolated antibody fragment, antibody-drug conjugate, nucleic acid molecule, host cell, and pharmaceutical composition
专利权人:
MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT
发明人:
FELIX ODEN,OLIVER DAUMKE,STEPHEN MARINO
申请号:
BR112016024546
公开号:
BR112016024546A2
申请日:
2015.04.30
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The invention relates to antibodies or humanized antibody fragments that bind to cd269 (bcma), thereby disrupting the interaction between cd269 and its native ligands (baff and april) and their use in the treatment of plasma cell mediated diseases such as like multiple myeloma and autoimmune diseases.a invenção se refere a anticorpos ou fragmentos de anticorpos humanizados que se ligam ao cd269 (bcma), interrompendo assim a interação entre o cd269 e seus ligantes nativos (baff e april) e ao seu uso no tratamento de doenças mediadas por células plasmáticas, tais como o mieloma múltiplo e doenças autoimunes.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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