Timo VESIKARI,Vesna BLAZEVIC,Kirsi NURMINEN,Leena HUHTI,Suvi LAPPALAINEN,Eeva JOKELA
申请号：
US13269326
公开号：
US20120093884A1
申请日:
2011.10.07
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to a combined norovirus and rotavirus vaccine for prevention of norovirus and rotavirus infection and/or viral-induced diarrheal and vomiting diseases in man. More specifically, the invention comprises a method of preparing combination vaccine compositions comprising norovirus and rotavirus antigens, in particular mixtures of norovirus VLPs and rotavirus recombinant VP6 protein or double-layered VP2/VP6 VLPs. In addition, the invention relates to methods of inducing an immune response.
