A composition for topical application comprises a base at 80 to 99% volume/volume of the composition, in which is dispersed: (i) elemental silver as a colloidal suspension, at from 1x10-5 to 1x10-2 by weight/volume of the composition; and (ii) a plant extract in an amount of from 1.0% to 10.0% weight/volume. The plant extract is derived from Matricaria recutita, Calendula officinalis, Aloe Vera, Chelidonium majus, Thuja occidentalis, and Mahonia aquifolium. The composition may be used for the treatment of moles (nevi).