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COMBINATION THERAPY WITH GLUTAMINASE INHIBITORS
专利权人:
Calithera Biosciences; Inc.
发明人:
Susanne M. Steggerda,Andrew L. MacKinnon,Mirna L. Rodriguez,Dong Zhang,Francesco Parlati
申请号:
US15585523
公开号:
US20170333430A1
申请日:
2017.05.03
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention relates to methods of treating cancer, myeloproliferative diseases, or immunological or neurological diseases with a combination of a glutaminase inhibitor and an anticancer agent such as an enzyme inhibitor (such as a kinase inhibitor), a mitotic inhibitor, a DNA-modifying agent, or a cytidine analog. The invention further relates to methods of treating cancer, myeloproliferative diseases, or immunological or neurological diseases that are resistant to one or more anticancer agents.
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