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Conjugation reagents
专利权人:
发明人:
Antony Godwin,Stephen Brocchini
申请号:
US13919217
公开号:
US09650331B2
申请日:
2013.06.17
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The invention provides compound of the general formula:in which each X independently represents a polymer chain n represents an integer greater than 1 Q represents a linker Y represents an amide group and Z represents either —CH.(CH2L)2 or —C(CH2L)(═CH2), in which each L independently represents a leaving group. The compounds are useful reagents for the conjugation of polymers to proteins, the resulting conjugates being novel and also forming part of the invention.
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