A high-throughput system for processing biological material that comprises: a tray that supports a functionally-closed fluid path subsystem comprising, a vessel for containing and enabling the biological material to separate into two or more distinct submaterials one or more receptacles to receive one or more of the submaterials from the vessel a filtration device a conduit through which one or more submaterials are transported between at least the vessel and the filtration device and a first engagement structure a processing unit comprising, a pumping device for moving one or more of the submaterials between at least the vessel and the filtration device via the conduit a second engagement structure corresponding to the first engagement structure a locking mechanism for at least temporarily holding the tray in a fixed position relative to the processing unit a control device that automatically starts and stops the pumping device in response to one or more commands.
