Matthias Hoffmann,Georg Dahmann,Christian Gnamm,Daniel Robert Fandrick,John Scott,Clive McCarthy
申请号:
US15809163
公开号:
US10155751B2
申请日:
2017.11.10
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to new substituted heteroaryls of formula 1or of formula 1′wherein A is either N or CH,wherein R2 is selected from the group consisting of —C1-3-alkyl, —C1-3-haloalkyl, F, Br, Cl,wherein Y is selected from —O— or —CH2—,and wherein R3 is defined as in claim 1, and the pharmaceutically acceptable salts thereof,and the use of these aforementioned compounds for the treatment of diseases such as asthma, COPD, allergic rhinitis, allergic dermatitis, lupus erythematodes, lupus nephritis and rheumatoid arthritis.