KELER, TIBOR,HE, LIZHEN,RAMAKRISHNA, VENKY,VITALE, LAURA A
申请号:
NZ58555608
公开号:
NZ585556A
申请日:
2008.11.07
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is an isolated monoclonal antibody which binds to human Dendritic and Epithelial Cell 205 receptor (DEC-205) comprising a heavy chain variable region comprising SEQ ID NO:28 and a light chain variable region comprising SEQ ID NO:34. Further disclosed is an isolated monoclonal antibody which binds to human Dendritic and Epithelial Cell 205 receptor (DEC-205) comprising a heavy chain variable region CDR1 comprising SEQ ID NO: 29 a heavy chain variable region CDR2 comprising SEQ ID NO: 30 a heavy chain variable region CDR3 comprising SEQ ID NO: 31 a light chain variable region CDR1 comprising SEQ ID NO: 35 a light chain variable region CDR2 comprising SEQ ID NO: 36 and a light chain variable region CDR3 comprising SEQ ID NO: 37. Further disclosed is an isolated monoclonal antibody which binds to human Dendritic and Epithelial Cell 205 receptor (DEC-205) comprising a heavy chain variable region and a light chain variable region encoded bySEQ ID NOs: 26 and 32, respectively.