aminopyrazine, pharmaceutical formulation, process for the preparation of an aminopyrazine derivative, and intermediate.

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专利权人:

UNIVERSITY OF CAPE TOWN;MMV MEDICINES FOR MALARIA VENTURE

发明人:

DAVID WATERSON,KELLY CHIBALE,MICHAEL JOHN WITTY,YASSIR YOUNIS

申请号：

BR112014020212

公开号：

BR112014020212A8

申请日:

2013.02.15

申请国别(地区):

BR

年份:

2018

代理人:

摘要：

The present invention is related to a use of aminopyrazine derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to aminopyrazine derivatives useful for the preparation of a pharmaceutical formulation for the inhibition of malaria parasite proliferation. In one embodiment, the invention provides aminopyrazine derivatives having the following formula:

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