INHIBIDORES DE GLUCOSILCERAMIDA SINTASA
- 专利权人:
- GENZYME CORPORATION
- 发明人:
- MARSHALL JOHN,CHENG SENG,SIEGEL CRAIG,WILLIS CHRIS,COPELAND DIANE P.,HARIANAWALA ABIZER,SKELL JEFFREY,KOCHLING JIANMEI,PALACE GERARD,PETER-SCHMITT JUDITH,BHARDWAJ RENU,LIU HARLAN
- 申请号:
- CL2016002589
- 公开号:
- CL2016002589A1
- 申请日:
- 2016.10.12
- 申请国别(地区):
- CL
- 年份:
- 2017
- 代理人:
- 摘要:
- < p > use of compound & nbsp n - [(1R, 2R) - 1 - (2,3 Dihydro 1,4 - - 6 - - benzodioxin il) - 1 - hydroxy - 3 - 1 - 2 - ilpropan - pyrrolidin-3-yl] - il octanamide or one of its Salts such as hemitartrato, to treat a subject with Gaucher disease, Fabry disease, which has been examined to determine if its a metabolizer L Sorry, Intermediate or extensive P450. < \/ p >
USO DEL COMPUESTO  N-[(1R,2R)-1-(2,3-DIHIDRO-1,4-BENZODIOXIN-6-IL)-1-HIDROXI-3-PIRROLIDIN-1-ILPROPAN-2-IL]OCTANAMIDA O UNA DE SUS SALES TAL COMO HEMITARTRATO, PARA TRATAR UN SUJETO CON EMFERMEDAD DE GAUCHER O ENFERMEDAD DE FABRY QUE HA SIDO EXAMINADO PARA DETERMINAR SI ES UN METABOLIZADOR LENTO, INTERMEDIO O EXTENSIVO DE P450.
- 来源网站:
- 中国工程科技知识中心